Azalanstat

• Description :

  Azalanstat is an imidazole-dioxolane derivate that is a lanosterol 14-α demethylase inhibitor. Azalanstat is also a HO-1 (IC50 = 5.5 µM) and HO-2 (IC50 = 24.5 µM) inhibitor[1].

• Product Name Alternative :

  RS-21607

• UNSPSC :

  12352005

• Target :

  Cytochrome P450; Reactive Oxygen Species (ROS)

• Type :

  Reference compound

• Related Pathways :

  Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB

• Field of Research :

  Infection; Inflammation/Immunology

• Assay Protocol :

  https://www.medchemexpress.com/azalanstat.html

• Smiles :

  ClC(C=C1)=CC=C1CC[C@]2(O[C@@H](CO2)CSC3=CC=C(C=C3)N)CN4C=CN=C4

• Molecular Formula :

  C22H24ClN3O2S

• Molecular Weight :

  429.96

• References & Citations :

  [1]Salerno L, et al. Progress in the development of selective heme oxygenase-1 inhibitors and their potential therapeutic application. Eur J Med Chem. 2019 Apr 1;167:439-453.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  Phase 2

• CAS Number :

  [143393-27-5]