HG-7-86-01

• UNSPSC Description:

  HG-7-86-01 (Compound 26) is type II tyrosine kinase inhibitor. HG-7-86-01 has anti-proliferative activity[1].

• Target Antigen:

  Bcr-Abl

• Type:

  Reference compound

• Related Pathways:

  Protein Tyrosine Kinase/RTK

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Cancer; Inflammation/Immunology

• Assay Protocol:

  https://www.medchemexpress.com/hg-7-86-01.html

• Solubility:

  DMSO : 5 mg/mL (ultrasonic;warming;heat to 60°C)

• Smiles:

  O=C(C1CC1)NC2=NC3=CC=C(C4=CC=CC(C(NC5=CC(N6C=NC(C)=C6)=CC(C(F)(F)F)=C5)=O)=C4)N=C3S2

• Molecular Weight:

  562.57

• References & Citations:

  [1]Choi HG, et al. Development of 'DFG-out' inhibitors of gatekeeper mutant kinases. Bioorg Med Chem Lett. 2012 Aug 15;22(16):5297-302.

• Shipping Conditions:

  Room Temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  1258391-14-8