Ac-WEHD-AFC

• Description:

  Ac-WEHD-AFC is a fluorogenic caspase-1 substrate. Ac-WEHD-AFC can measure caspase-1 fluorogenic activity and can be used for the research of tumor and inflammation[1].

• UNSPSC:

  12352209

• Target:

  Caspase; Fluorescent Dye

• Type:

  Peptides

• Related Pathways:

  Apoptosis; Others

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Cancer; Inflammation/Immunology

• Assay Protocol:

  https://www.medchemexpress.com/ac-wehd-afc.html

• Solubility:

  10 mM in DMSO

• Smiles:

  FC(F)(C(C(C(O1)=C2)=CC=C2NC([C@H](CC(O)=O)NC([C@@H](NC([C@H](CCC(O)=O)NC([C@@H](NC(C)=O)CC3=CNC4=CC=CC=C34)=O)=O)CC5=CN=CN5)=O)=O)=CC1=O)F

• Molecular Formula:

  C38H37F3N8O11

• Molecular Weight:

  838.74

• References & Citations:

  [1]Katherine Labbé, et al. Cellular inhibitors of apoptosis proteins cIAP1 and cIAP2 are required for efficient caspase-1 activation by the inflammasome. Immunity

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Peptides

• Clinical Information:

  No Development Reported

• Isoform:

  Caspase 1

• CAS Number:

  [210344-99-3]