Bml-278

CAT: 0400-SIH-349-5MGSize: 5 mgDry Ice: NoHazardous: No

CAT#:0400-SIH-349-5MGSize:5 mg

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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Background

A structurally novel activator of SIRT1 (EC150=1 µM). Displays selectivity over SIRT2 and 3 (EC150=25 and 50 µM respectively). Cell permeable.

Description

SIRT1 activator

Product Name Alternative

N-Benzyl-3,5-dicarbethoxy-4-phenyl-1,4-dihydropyridine

UNSPSC

41116105

Type

Inhibitor

Source

Synthetic

Field of Research

Cell Signaling | Epigenetics and Nuclear Signaling

Purity

>98% (TLC), NMR conforms

Weight

0.005

Format

Off-White Solid

Solubility

Soluble in 5 mg/ml DMSO

Molecular Formula

C24H25NO4

Molecular Weight

391.5

Precautions

Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.

References & Citations

1. Mai A., et al. (2009) J. Med. Chem. 52: 5496.

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