Bml-210

• Background:

  A novel non-hydroxamic acid HDAC inhibitor. IC50=5-10 µM (HeLa nuclear extract). Induces growth inhibition, proapoptotic and differentiation effects on human leukemia cell lines.

• Description:

  HDAC inhibitor

• Product Name Alternative:

  N1- (2-aminophenyl) -N8-phenyloctanediamide

• UNSPSC:

  41116105

• Type:

  Inhibitor

• Source:

  Synthetic

• Field of Research:

  Cell Signaling | Epigenetics and Nuclear Signaling | Cancer

• Purity:

  >98% (TLC), NMR conforms

• Weight:

  0.005

• Format:

  Tan Solid

• Solubility:

  Soluble in 25 mg/ml DMSO or 10 mg/ml Ethanol

• Molecular Formula:

  C20H25N3O2

• Molecular Weight:

  339.4

• Precautions:

  Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.

• References & Citations:

  1. Savickiene J., et al. (2006) Eur. J. Pharmacol. 549: 9. 2. Herman D., et al. (2006) Nature Chem. Biol. 10: 551.

• CAS Number:

  537034-17-6