Gamma Synuclein Monomers

• Background:

  Gamma synuclein is a neuronal protein found in peripheral and motor nerve systems. It has been implicated in the hippocampal axon pathology in Parkinson's Disease (1) . A change in the expression of gamma synuclein has been observed in the retina of patients with Alzheimer's disease (2) . Its expression in breast tumors is also a marker for tumor progression (3) .

• Description:

  Human Recombinant Gamma Synuclein Monomers

• Product Name Alternative:

  BCSG1 Protein Monomer, Breast cancer specific gene 1 Protein Monomer, Breast cancer specific Protein 1 Monomer, Gamma-synuclein Protein Monomer, Persyn Protein Monomer, PRSN Protein Monomer, SNCG Protein Monomer, SR Protein Monomer, Synoretin Protein Monomer, Synuclein gamma Protein Monomer, SYUG_HUMAN Protein Monomer

• UNSPSC:

  12352202

• UN Code:

  Non-hazardous

• Hazard Statement:

  Non-hazardous

• Gene ID:

  6623

• Swiss Prot:

  O76070

• Accession Number:

  NP_003078.2

• Cellular Locus:

  Cytoskeleton | Centrosome | Spindle | Perinuclear Region

• Expression System:

  E. coli

• Host:

  E. coli

• Origin Species:

  Human

• Target:

  Gamma Synuclein

• Conjugation:

  No tag

• Nature:

  Recombinant

• Applications:

  WB | SDS-PAGE | In vivo assay | In vitro assay

• Field of Research:

  Neuroscience | Neurodegeneration | Alzheimer's Disease | Tangles & Tau | Neuroscience | Neurodegeneration | Parkinson's Disease | Synuclein

• Purification Method:

  Ion-exchange Purified

• Purification:

  Ion-exchange Purified

• Limit Of Detection:

  Certified >95% pure using SDS-PAGE analysis. Low endotoxin <5 EU/mL @ 2mg/mL.

• Concentration:

  2 mg/ml

• Purity:

  >95%

• Weight:

  0

• Length:

  Full length

• Buffer:

  PBS pH 7.4

• Molecular Weight:

  13.33 kDa

• Precautions:

  Not for use in humans. Not for use in diagnostics or therapeutics. For research use only.

• Additionnal Information:

  For corresponding PFFs, see catalog# SPR-459

• References & Citations:

  1. Nishioka K., et al. (2010) Arch Neurol. 67(8): 970-975. 2. Surgucheva I., Newell K.L., Burns J., Surguchov A. (2014) Acta Neuropathol Commun. 2: 132. 3. Bruening. W., et al. (2000) Cancer. 88(9): 2154-2163. 4. Mukaetova-Ladinska E.B., et al. (2008) Dement Geriatr Cogn Disord. 26(1): 32-42.

• Shipping Conditions:

  Dry Ice. Shipping note: Product will be shipped separately from other products purchased in the same order.

• Storage Conditions:

  -80ºC

• Notes:

  For corresponding PFFs, see catalog# SPR-459

• Protein Length:

  Full length

• Background Reference 01:

  1. Nishioka K., et al. (2010) Arch Neurol. 67 (8) : 970-975. 2. Surgucheva I., Newell K.L., Burns J., Surguchov A. (2014) Acta Neuropathol Commun. 2: 132. 3. Bruening. W., et al. (2000) Cancer. 88 (9) : 2154-2163. 4. Mukaetova-Ladinska E.B., et al. (2008) Dement Geriatr Cogn Disord. 26 (1) : 32-42.

• Location:

  Cytoskeleton | Centrosome | Spindle | Perinuclear Region

• Immunogen Species:

  Human