Gamma Synuclein Monomers

• Background :

  Gamma synuclein is a neuronal protein found in peripheral and motor nerve systems. It has been implicated in the hippocampal axon pathology in Parkinson's Disease (1) . A change in the expression of gamma synuclein has been observed in the retina of patients with Alzheimer's disease (2) . Its expression in breast tumors is also a marker for tumor progression (3) .

• Description :

  Human Recombinant Gamma Synuclein Monomers

• Product Name Alternative :

  BCSG1 Protein Monomer, Breast cancer specific gene 1 Protein Monomer, Breast cancer specific Protein 1 Monomer, Gamma-synuclein Protein Monomer, Persyn Protein Monomer, PRSN Protein Monomer, SNCG Protein Monomer, SR Protein Monomer, Synoretin Protein Monomer, Synuclein gamma Protein Monomer, SYUG_HUMAN Protein Monomer

• UNSPSC :

  12352202

• UN Code :

  Non-hazardous

• Hazard Statement :

  Non-hazardous

• Gene ID :

  6623

• Swiss Prot :

  O76070

• Accession Number :

  NP_003078.2

• Cellular Locus :

  Cytoskeleton | Centrosome | Spindle | Perinuclear Region

• Expression System :

  E. coli

• Host :

  E. coli

• Origin Species :

  Human

• Target :

  Gamma Synuclein

• Conjugation :

  No tag

• Nature :

  Recombinant

• Applications :

  WB | SDS-PAGE | In vivo assay | In vitro assay

• Field of Research :

  Neuroscience | Neurodegeneration | Alzheimer's Disease | Tangles & Tau | Neuroscience | Neurodegeneration | Parkinson's Disease | Synuclein

• Purification Method :

  Ion-exchange Purified

• Purification :

  Ion-exchange Purified

• Limit Of Detection :

  Certified >95% pure using SDS-PAGE analysis. Low endotoxin <5 EU/mL @ 2mg/mL.

• Concentration :

  2 mg/ml

• Purity :

  >95%

• Weight :

  0

• Length :

  Full length

• Buffer :

  PBS pH 7.4

• Molecular Weight :

  13.33 kDa

• Precautions :

  Not for use in humans. Not for use in diagnostics or therapeutics. For research use only.

• Additionnal Information :

  For corresponding PFFs, see catalog# SPR-459

• References & Citations :

  1. Nishioka K., et al. (2010) Arch Neurol. 67(8): 970-975. 2. Surgucheva I., Newell K.L., Burns J., Surguchov A. (2014) Acta Neuropathol Commun. 2: 132. 3. Bruening. W., et al. (2000) Cancer. 88(9): 2154-2163. 4. Mukaetova-Ladinska E.B., et al. (2008) Dement Geriatr Cogn Disord. 26(1): 32-42.

• Shipping Conditions :

  Dry Ice. Shipping note: Product will be shipped separately from other products purchased in the same order.

• Storage Conditions :

  -80ºC

• Notes :

  For corresponding PFFs, see catalog# SPR-459

• Protein Length :

  Full length

• Background Reference 01 :

  1. Nishioka K., et al. (2010) Arch Neurol. 67 (8) : 970-975. 2. Surgucheva I., Newell K.L., Burns J., Surguchov A. (2014) Acta Neuropathol Commun. 2: 132. 3. Bruening. W., et al. (2000) Cancer. 88 (9) : 2154-2163. 4. Mukaetova-Ladinska E.B., et al. (2008) Dement Geriatr Cogn Disord. 26 (1) : 32-42.

• Location :

  Cytoskeleton | Centrosome | Spindle | Perinuclear Region

• Immunogen Species :

  Human