SKA-121

CAT: 0804-HY-107414-01Size: 5 mgDry Ice: NoHazardous: No
CAT#:0804-HY-107414-01Size:5 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
SKA-121 is a selective KCa3.1 activator. SKA-121 exhibits EC50s of 109 nM and 4.4 μM for KCa3.1 and KCa2.3, respectively.
CAS Number
[1820708-73-3]
UNSPSC
12352005
Target
Potassium Channel
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel
Applications
COVID-19-immunoregulation
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/SKA-121.html
Purity
99.69
Solubility
DMSO : ≥ 42.86 mg/mL
Smiles
NC1=NC2=CC(C)=C3C=CC=CC3=C2O1
Molecular Formula
C12H10N2O
Molecular Weight
198.22
References & Citations
[1]Coleman N, et al. New positive Ca2+-activated K+ channel gating modulators with selectivity for KCa3.1. Mol Pharmacol. 2014 Sep;86 (3) :342-57.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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