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TTR stabilizer L6

CAT: 0804-HY-126927Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-126927Size:1 Each
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Description
TTR stabilizer L6 (L6) binds to the T4 binding pocket of transthyretin (TTR), which can prevent the dissociation of TTR to monomer. TTR stabilizer L6 is promising for research of familial amyloid polyneuropathy[1].
CAS Number
881290-53-5
UNSPSC
12352005
Target
Transthyretin (TTR)
Type
Reference compound
Related Pathways
Neuronal Signaling
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/ttr-stabilizer-l6.html
Smiles
O=C1N(O)C(C2=CC=C(C(C3=CC=CC=C3)=O)C4=CC=CC1=C24)=O
Molecular Formula
C19H11NO4
Molecular Weight
317.29
References & Citations
[1]Yokoyama T, et al. Structural stabilization of transthyretin by a new compound, 6-benzoyl-2-hydroxy-1H-benzo[de]isoquinoline-1,3 (2H) -dione. J Pharmacol Sci. 2015 Dec;129 (4) :240-3.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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