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Axl-IN-16

CAT: 0804-HY-N12041Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-N12041Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Axl-IN-16 is a dual inhibitor of Axl/HIF. Axl-IN-16 induces fruiting body formation of Flammulina velutipes. Axl-IN-16 inhibits hypoxia-inducible factor activity and receptor tyrosine kinase expression[1].
UNSPSC
12352005
Target
HIF/HIF Prolyl-Hydroxylase; TAM Receptor
Type
Natural Products
Related Pathways
Metabolic Enzyme/Protease; Protein Tyrosine Kinase/RTK
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/axl-in-16.html
Solubility
10 mM in DMSO
Smiles
ClC1=C(OC)C=C(C(OC[C@@H](O)[C@@H](O)[C@H](O)CO)=O)C=C1OC
Molecular Formula
C14H19ClO8
Molecular Weight
350.75
References & Citations
[1]Wu J, et al. "Fruiting Liquid" of Mushroom-Forming Fungi, A Novel Source of Bioactive Compounds - Fruiting-Body Inducer and HIF and Axl Inhibitors. J Agric Food Chem. 2023 Sep 13;71 (36) :13338-13345.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported
Isoform
Axl

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