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MDM2-IN-24

CAT: 0804-HY-163275Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-163275Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
MDM2-IN-24 (compound A3f) exhibits MDM2-inhibiting and MDMX-activating properties in triple-negative breast cancer (TNBC) cells, with apoptotic and anti-proliferative activities[1].
UNSPSC
12352005
Target
Apoptosis; MDM-2/p53
Type
Reference compound
Related Pathways
Apoptosis
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/mdm2-in-24.html
Solubility
10 mM in DMSO
Smiles
BrC1=C2C=CC=CC2=C(C[P+](C3=CC=CC=C3)(C4=CC=CC=C4)C5=CC=CC=C5)C6=CC=CC=C16.[Br-]
Molecular Formula
C33H25Br2P
Molecular Weight
612.33
References & Citations
[1]Feng Y, et al., Targeting G-rich sequence to regulate the transcription of murine double minute (MDM) genes in triple-negative breast cancers. Eur J Med Chem. 2024 Jan 25;267:116156.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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