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MDM2-IN-1

CAT: 0804-HY-130684-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-130684-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
MDM2-IN-1 (Compound 30) is a synthetic MDM2-p53 interaction (MDM2) inhibitor and contains the trans-configuration. MDM2-IN-1 can be used for the study of osteosarcoma[1].
CAS Number
1410737-09-5
UNSPSC
12352005
Target
MDM-2/p53
Type
Reference compound
Related Pathways
Apoptosis
Applications
Neuroscience-Neurodegeneration
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/mdm2-in-1.html
Purity
98.02
Solubility
DMF : 10 mg/mL (ultrasonic; warming; heat to 60°C) |DMSO : 22 mg/mL (ultrasonic; warming; heat to 80°C)
Smiles
O=C([C@H](N1)[C@H](C2=CC=CC(Cl)=C2F)[C@]3(C(NC4=C3C=CC(Cl)=C4)=O)C51CCCCC5)O
Molecular Formula
C23H21Cl2FN2O3
Molecular Weight
463.33
References & Citations
[1]Aguilar A, et al. Design of chemically stable, potent, and efficacious MDM2 inhibitors that exploit the retro-mannich ring-opening-cyclization reaction mechanism in spiro-oxindoles. J Med Chem. 2014 Dec 26;57 (24) :10486-98.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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