Avenanthramide C

• Description:

  Avenanthramide C is an orally active avenanthramide that can be isolated from oat seeds. Avenanthramide C decreases the protein expression of cleaved caspase-3 and increases the expression of p-GSK3β (Ser9) and IL-10 levels. Avenanthramide C has the potential for the research of Alzheimer’s disease[1].

• UNSPSC:

  12352005

• Hazard Statement:

  H302, H315, H319, H335

• Target:

  Interleukin Related

• Type:

  Natural Products

• Related Pathways:

  Immunology/Inflammation

• Applications:

  Neuroscience-Neurodegeneration

• Field of Research:

  Neurological Disease

• Assay Protocol:

  https://www.medchemexpress.com/avenanthramide-c.html

• Purity:

  98.90

• Solubility:

  DMSO : 50 mg/mL (ultrasonic)

• Smiles:

  O=C(C1=CC(O)=CC=C1NC(/C=C/C2=CC=C(C(O)=C2)O)=O)O

• Molecular Formula:

  C16H13NO6

• Molecular Weight:

  315.28

• Precautions:

  H302, H315, H319, H335

• References & Citations:

  [1]Matsukawa T, et al. Occurrence of avenanthramides and hydroxycinnamoyl-CoA:hydroxyanthranilate N-hydroxycinnamoyltransferase activity in oat seeds. Z Naturforsch C J Biosci. 2000 Jan-Feb;55 (1-2) :30-6. |[2]Ramasamy VS, et al. Avenanthramide-C Restores Impaired Plasticity and Cognition in Alzheimer's Disease Model Mice. Mol Neurobiol. 2020 Jan;57 (1) :315-330.Ramasamy VS, et al. Avenanthramide-C Restores Impaired Plasticity and Cognition in Alzheimer's Disease Model Mice. Mol Neurobiol. 2020 Jan;57 (1) :315-330.

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  -20°C, 3 years (Powder)

• Scientific Category:

  Natural Products

• Clinical Information:

  No Development Reported

• CAS Number:

  [116764-15-9]