Avenanthramide A
CAT:
804-HY-114977-02
Size:
10 mg
Price:
Ask
- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
Avenanthramide A
- Product Name Alternative: Monobromobimane
- CAS Number: 108605-70-5
- UNSPSC Description: Avenanthramide A is a phytoalexin, which can be found in oats (Avena sativa L.). Avenanthramide A targets the RNA helicase DDX3, leads to mitochondrial swelling and increased ROS production, and induces apoptosis in CRC cells. Avenanthramide A exhibits antitumor efficacy in mouse model. Avenanthramide A orally active[1].
- Target Antigen: Apoptosis; Reactive Oxygen Species
- Type: Natural Products
- Related Pathways: Apoptosis;Immunology/Inflammation;Metabolic Enzyme/Protease;NF-κB
- Field of Research: Cancer
- Assay Protocol: https://www.medchemexpress.com/avenanthramide-a.html
- Purity: 99.20
- Solubility: DMSO : 100 mg/mL (ultrasonic)
- Smiles: O=C(C1=CC(O)=CC=C1NC(/C=C/C2=CC=C(C=C2)O)=O)O
- Molecular Weight: 299.28
- References & Citations: [1]Fu R, et al., Avenanthramide A triggers potent ROS-mediated anti-tumor effects in colorectal cancer by directly targeting DDX3. Cell Death Dis. 2019 Aug 7;10(8):593.
- Shipping Conditions: Room Temperature
- Storage Conditions: 4°C (Powder, protect from light)
- Clinical Information: No Development Reported