SSR504734 (free base)

• UNSPSC Description:

  SSR504734 free base is an orally active, selective and reversible inhibitor of human, rat, and mouse GlyT1 (IC50=18, 15, and 38?nM, respectively). SSR504734 free base shows anti-schizophrenia, anti-anxiety and anti-depression activities[1].

• Target Antigen:

  GlyT

• Type:

  Reference compound

• Related Pathways:

  Membrane Transporter/Ion Channel;Neuronal Signaling

• Field of Research:

  Neurological Disease

• Assay Protocol:

  https://www.medchemexpress.com/ssr504734-free-base.html

• Smiles:

  O=C(C1=CC=CC(C(F)(F)F)=C1Cl)NC[C@H]2N(CCCC2)C3=CC=CC=C3

• Molecular Weight:

  396.83

• References & Citations:

  [1]Ronan Depoortère, et al. Neurochemical, electrophysiological and pharmacological profiles of the selective inhibitor of the glycine transporter-1 SSR504734, a potential new type of antipsychotic. Neuropsychopharmacology. 2005 Nov;30(11):1963-85.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  742693-38-5