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SSR504734

CAT: 0804-HY-10715-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-10715-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
SSR504734 is an orally active, selective and reversible inhibitor of human, rat, and mouse GlyT1 (IC50=18, 15, and 38 nM, respectively) . SSR504734 shows anti-schizophrenia, anti-anxiety and anti-depression activities[1].
CAS Number
615571-23-8
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
GlyT
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/ssr504734.html
Purity
99.82
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C(C1=C(C(C(F)(F)F)=CC=C1)Cl)N[C@H]([C@]2([H])CCCCN2)C3=CC=CC=C3.Cl
Molecular Formula
C20H21Cl2F3N2O
Molecular Weight
433.29
Precautions
H302, H315, H319, H335
References & Citations
[1]Ronan Depoortère, et al. Neurochemical, electrophysiological and pharmacological profiles of the selective inhibitor of the glycine transporter-1 SSR504734, a potential new type of antipsychotic. Neuropsychopharmacology. 2005 Nov;30 (11) :1963-85.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture and light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
GlyT1

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