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Ambroxol (Standard)

CAT: 0804-HY-B1039R-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-B1039R-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Ambroxol (Standard) is the analytical standard of Ambroxol. This product is intended for research and analytical applications. Ambroxol (NA-872), an active metabolite of the proagent Bromhexine, has potent expectorant effects. Ambroxol is a glucocerebrosidase (GCase) chaperone and increases glucocerebrosidase activity. Ambroxol induces lung autophagy and has the potential for Parkinson disease and neuronopathic Gaucher disease research[1][2].
CAS Number
18683-91-5
Product Name Alternative
NA-872 (Standard)
UNSPSC
12352005
Target
Autophagy; Glycosidase; Reference Standards
Type
Reference Standards
Related Pathways
Autophagy; Metabolic Enzyme/Protease; Others
Field of Research
Metabolic Disease; Neurological Disease
Assay Protocol
https://www.medchemexpress.com/ambroxol-standard.html
Smiles
O[C@H]1CC[C@H](NCC2=CC(Br)=CC(Br)=C2N)CC1
Molecular Formula
C13H18Br2N2O
Molecular Weight
378.10
References & Citations
[1]Vojo Deretic, et al. Enhancement of lung levels of antibiotics by ambroxol and bromhexine. Expert Opin Drug Metab Toxicol. 2019 Mar;15 (3) :213-218.|[2]Anna Migdalska-Richards, et al. Ambroxol effects in glucocerebrosidase and α-synuclein transgenic mice. Ann Neurol. 2016 Nov;80 (5) :766-775.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards

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