Products for Research Use Only
RegisterLogin

NMDA-IN-1

CAT: 0804-HY-12962-01Size: 1 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-12962-01Size:1 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
NMDA-IN-1 is a potent and NR2B-selective NMDA antagonist with Ki of 0.85 nM; NR2B Ca2+ influx IC50 is 9.7 nM; no activities on NR2A, NR2C, NR2D, hERG-channel and α1-adrenergic receptor.
CAS Number
700878-19-9
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
IGluR
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel; Neuronal Signaling
Applications
Neuroscience-Neurodegeneration
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/NMDA-IN-1.html
Purity
98.98
Solubility
DMSO : 12.5 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
OC1=CC=C2N=C(CN3CCC(CC4=CC=CC=C4F)CC3)NC2=C1.[H]Cl
Molecular Formula
C20H23ClFN3O
Molecular Weight
375.87
Precautions
H302, H315, H319, H335
References & Citations
[1]McCauley JA, et al. NR2B-selective N-methyl-D-aspartate antagonists: synthesis and evaluation of 5-substituted benzimidazoles. J Med Chem. 2004 Apr 8;47 (8) :2089-96.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
NMDA Receptor

Related Products

CatalogName
HY-17551-01NMDA
HY-147352NMDA receptor potentiator-1
HY-145897NMDA-IN-2
HY-126123-01NR2B-selective NMDA receptor antagonist 1
HY-107717MNI-caged-NMDA
HY-107698PMPA (NMDA antagonist)
HY-172121NMDA agonist 2
HY-155185NMDA receptor antagonist 7
HY-155049NMDA receptor antagonist 6
HY-143390NMDA receptor modulator 2

Alternative Products

CatalogName
MBS131240-01NMDA-IN-1
A21419-200NMDA-IN-1 200mg
A21419-5NMDA-IN-1 5mg
A21419-1NMDA-IN-1 1mg
344757-01NMDAζ1 discontinued
B0692-01NMDAζ1 Antibody
T204880-01NMDA agonist 1
A21419-100NMDA-IN-1 100mg
A21419-50NMDA-IN-1 50mg
N2904-34NMDA 1 Receptor

Popular Products