EIF4B Polyclonal Antibody

• Background :

  Required for the binding of mRNA to ribosomes. Functions in close association with EIF4-F and EIF4-A. Binds near the 5'-terminal cap of mRNA in presence of EIF-4F and ATP. Promotes the ATPase activity and the ATP-dependent RNA unwinding activity of both EIF4-A and EIF4-F.

• Description :

  Rabbit Anti-eIF4B Polyclonal Antibody

• Product Name Alternative :

  EIF4B; Eukaryotic translation initiation factor 4B; eIF-4B

• Gene ID :

  1975

• Accession Number :

  P23588

• Reactivity :

  Human, Mouse

• Immunogen :

  Synthesized peptide derived from human eIF4B around the non-phosphorylation site of S422

• Clonality :

  Polyclonal

• Tag :

  Eukaryotic translation initiation factor 4B

• Applications :

  WB, IHC, IF, ELISA

• Purification Method :

  The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• Concentration :

  1 mg/ml

• Molecular Weight :

  70kD

• Precautions :

  The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

• Shipping Conditions :

  Gel pack with blue ice.

• Storage Conditions :

  Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

• Notes :

  EIF4B Polyclonal Antibody detects endogenous levels of eIF4B protein.

• Observed Molecular Weight :

  70

• Formulation :

  Liquid solution

• Buffer pH :

  Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• Applications Notes :

  Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000; IHC 1:100-1:300; IF 1:200-1:1000; ELISA 1:5000; Not yet tested in other applications.

• Other Product Names :

  EIF4B; Eukaryotic translation initiation factor 4B; eIF-4B

• Tested Applications :

  WB, IHC, IF, IP, ELISA

• Host or Source :

  Rabbit

• Accession Number URL :

  http://www.uniprot.org/uniprot/P23588

• CAS Number :

  9007-83-4

• Isotype :

  Rabbit IgG