ApoA-I Polyclonal Antibody

CAT: 0749-ABP53170-01Size: 30 µLDry Ice: NoHazardous: No
CAT#:0749-ABP53170-01Size:30 µL
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Background
APOA1 encodes apolipoprotein A-I, which is the major protein component of high density lipoprotein (HDL) in plasma. The encoded preproprotein is proteolytically processed to generate the mature protein, which promotes cholesterol efflux from tissues to the liver for excretion, and is a cofactor for lecithin cholesterolacyltransferase (LCAT), an enzyme responsible for the formation of most plasma cholesteryl esters. This gene is closely linked with two other apolipoprotein genes on chromosome 11. Defects in this gene are associated with HDL deficiencies, including Tangier disease, and with systemic non-neuropathic amyloidosis. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein.
Description
Rabbit Anti-ApoA-I Polyclonal Antibody
CAS Number
9007-83-4
Product Name Alternative
APOA1; Apolipoprotein A-I; Apo-AI; ApoA-I; Apolipoprotein A1
Gene ID
335
Accession Number
P02647
Reactivity
Human, Mouse
Immunogen
Synthesized peptide derived from the Internal region of human ApoA-I
Clonality
Polyclonal
Tag
Apolipoprotein A-I
Applications
WB, IHC, IF, ELISA
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Molecular Weight
31kD
Precautions
The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Shipping Conditions
Gel pack with blue ice.
Storage Conditions
Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Notes
ApoA-I Polyclonal Antibody detects endogenous levels of ApoA-I protein.
Formulation
Liquid solution
Buffer pH
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Applications Notes
Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000; IHC: 1:100-1:300; ELISA 1:20000; IF 1:50-200
Other Product Names
APOA1; Apolipoprotein A-I; Apo-AI; ApoA-I; Apolipoprotein A1
Tested Applications
WB, IHC, IF, IP, ELISA
Host or Source
Rabbit
Accession Number URL
http://www.uniprot.org/uniprot/P02647
Isotype
Rabbit IgG

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