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Neurophysin I Polyclonal Antibody

CAT: 0749-ABP55453-01Size: 30 µLDry Ice: NoHazardous: No
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CAT#:0749-ABP55453-01Size:30 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
OXT encodes a precursor protein that is processed to produce oxytocin and neurophysin I. Oxytocin is a posterior pituitary hormone which is synthesized as an inactive precursor in the hypothalamus along with its carrier protein neurophysin I. Together with neurophysin, it is packaged into neurosecretory vesicles and transported axonally to the nerve endings in the neurohypophysis, where it is either stored or secreted into the bloodstream. The precursor seems to be activated while it is being transported along the axon to the posterior pituitary. This hormone contracts smooth muscle during parturition and lactation. It is also involved in cognition, tolerance, adaptation and complex sexual and maternal behaviour, as well as in the regulation of water excretion and cardiovascular functions.
Description
Rabbit Anti-Neurophysin I Polyclonal Antibody
CAS Number
9007-83-4
Product Name Alternative
OXT; OT; Oxytocin-neurophysin 1; OT-NPI
Gene ID
5020
Accession Number
P01178
Reactivity
Human, Rat
Immunogen
Synthesized peptide derived from the Internal region of human Neurophysin I
Clonality
Polyclonal
Tag
Oxytocin-neurophysin 1
Applications
WB, IHC, IF, ELISA
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Molecular Weight
19kD
Precautions
The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Shipping Conditions
Gel pack with blue ice.
Storage Conditions
Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Notes
Neurophysin I Polyclonal Antibody detects endogenous levels of Neurophysin I protein.
Observed Molecular Weight
19
Formulation
Liquid solution
Buffer pH
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Applications Notes
Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000; IHC 1:100-1:300; ELISA 1:20000; IF 1:50-200
Other Product Names
OXT; OT; Oxytocin-neurophysin 1; OT-NPI
Tested Applications
WB, IHC, IF, IP, ELISA
Host or Source
Rabbit
Accession Number URL
http://www.uniprot.org/uniprot/P01178
Isotype
Rabbit IgG

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