Naringenin chalcone

• UNSPSC Description:

  Naringenin chalcone is an intermediate in flavonol biosynthesis and is spontaneously metabolized into naringenin (NAR) by chalcone isomerase. Naringenin chalcone is an orally active anti-inflammatory and antiallergic agent[1].

• Target Antigen:

  Others

• Type:

  Natural Products

• Related Pathways:

  Others

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Inflammation/Immunology

• Assay Protocol:

  https://www.medchemexpress.com/naringenin-chalcone.html

• Purity:

  99.29

• Solubility:

  DMSO : 50 mg/mL (ultrasonic)|Methanol : ≥ 25 mg/mL

• Smiles:

  OC(C=C1)=CC=C1/C=C/C(C2=C(C=C(O)C=C2O)O)=O

• Molecular Weight:

  272.25

• References & Citations:

  [1]Escribano-Ferrer E, et al. In Vivo Anti-inflammatory and Antiallergic Activity of Pure Naringenin, Naringenin Chalcone, and Quercetin in Mice.J Nat Prod. 2019 Feb 22;82(2):177-182.|[2]Iwamura C, Shinoda K, Yoshimura M, Watanabe Y, Obata A, Nakayama T. Naringenin chalcone suppresses allergic asthma by inhibiting the type-2 function of CD4 T cells. Allergol Int. 2010;59(1):67-73. |[3]Hirai S, Kim YI, Goto T, et al. Inhibitory effect of naringenin chalcone on inflammatory changes in the interaction between adipocytes and macrophages. Life Sci. 2007;81(16):1272-1279.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  4°C (Powder, protect from light)

• Clinical Information:

  No Development Reported

• CAS Number:

  73692-50-9