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Naringenin (Standard)

CAT: 0804-HY-N0100RSize: InquireDry Ice: NoHazardous: No
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CAT#:0804-HY-N0100RSize:Inquire
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
480-41-1
UNSPSC Description
Naringenin (Standard) is the analytical standard of Naringenin. This product is intended for research and analytical applications. Naringenin is the predominant flavanone in Citrus reticulata Blanco; displays strong anti-inflammatory and antioxidant activities. Naringenin has anti-dengue virus (DENV) activity.
Target Antigen
Dengue virus; Endogenous Metabolite; Influenza Virus; PPAR; Reactive Oxygen Species
Type
Reference compound
Related Pathways
Anti-infection;Cell Cycle/DNA Damage;Immunology/Inflammation;Metabolic Enzyme/Protease;NF-κB;Vitamin D Related/Nuclear Receptor
Field of Research
Cancer; Infection; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/naringenin-standard.html
Smiles
O=C1C[C@@H](C2=CC=C(O)C=C2)OC3=CC(O)=CC(O)=C13
Molecular Weight
272.25
References & Citations
[1]Arul D, et al. Naringenin (citrus flavonone) induces growth inhibition, cell cycle arrest and apoptosis in human hepatocellular carcinoma cells. Pathol Oncol Res. 2013 Oct;19(4):763-70.|[2]Ahamad MS, et al. Induction of apoptosis and antiproliferative activity of naringenin in human epidermoid carcinomacell through ROS generation and cell cycle arrest. PLoS One. 2014 Oct 16;9(10):e110003.|[3]Cho KW, et al. Dietary naringenin increases hepatic peroxisome proliferators-activated receptor α proteinexpression and decreases plasma triglyceride and adiposity in rats. Eur J Nutr. 2011 Mar;50(2):81-8.|[4]Mulvihill EE, et al. Naringenin prevents dyslipidemia, apolipoprotein B overproduction, and hyperinsulinemia in LDLreceptor-null mice with diet-induced insulin resistance. Diabetes. 2009 Oct;58(10):2198-210.|[5]Chen S, et al. Naringenin inhibits TNF-α induced VSMC proliferation and migration via induction of HO-1. Food Chem Toxicol. 2012 Sep;50(9):3025-31.|[6]Frabasile S, et al. The citrus flavanone naringenin impairs dengue virus replication in human cells. Sci Rep. 2017 Feb 3;7:41864.
Shipping Conditions
Room temperature

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