SEC24A Recombinant Rabbit Monoclonal Antibody [PSH04-36]

SEC24A Recombinant Rabbit Monoclonal Antibody [PSH04-36]

• Description: The protein encoded by this gene belongs to a family of proteins that are homologous to yeast Sec24. This protein is a component of coat protein II (COPII)-coated vesicles that mediate protein transport from the endoplasmic reticulum. COPII acts in the cytoplasm to promote the transport of secretory, plasma membrane, and vacuolar proteins from the endoplasmic reticulum to the golgi complex. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules for their transport to the Golgi complex. Plays a central role in cargo selection within the COPII complex and together with SEC24B may have a different specificity compared to SEC24C and SEC24D. May package preferentially cargos with cytoplasmic DxE or LxxLE motifs and may also recognize conformational epitopes.
• Product Name Alternative: protein transport protein Sec24A antibody SEC24 family member A S cerevisiae antibody SEC24 related gene family member A antibody SEC24 related protein A antibody SEC24 S cerevisiae related gene family member A antibody
• Abbreviation: SEC24A
• CAS Number: 9000-83-3
• Swiss Prot: O95486 Human, Q3U2P1 Mouse,
• Cellular Locus: Cytoplasmic vesicle, COPII-coated vesicle membrane, Endoplasmic reticulum membrane, Cytoplasm, cytosol.
• Host: Rabbit
• Species Reactivity: Human, Mouse, Rat, Monkey
• Immunogen: Recombinant protein within human SEC24A aa 1-350 / 1,093.
• Isotype: IgG
• Clone: PSH04-36
• Conjugation: Non-conjugated
• Type: Recombinant Rabbit monoclonal Antibody
• Applications: WB, IF-Cell, IHC-P, FC
• Positive Control: Caco-2 cell lysate, HEK-293 cell lysate, HeLa cell lysate, U-87 MG cell lysate, COS-1 cell lysate, Caco-2, human b-cell lymphoma tissue, human stomach tissue, mouse stomach tissue, rat stomach tissue.
• Concentration: 1 mg/mL
• Dilution: WB: 1:2,000 ;IF-Cell: 1:100 ;IHC-P: 1:200-1:1,000 ;FC: 1:1,000
• Purity: Protein A affinity purified.
• Form: Liquid
• Buffer: PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
• Molecular Weight: Predicted band size: 120 kDa
• Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
• Recombinant Antibody: Yes