Products for Research Use Only
RegisterLogin

ZBT7A rabbit pAb

CAT: 0855-ES11928-01Size: 50 µLDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0855-ES11928-01Size:50 µL
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Background
Function:Plays a key role in the instruction of early lymphoid progenitors to develop into B lineage by repressing T-cell instructive Notch signals (By similarity) . Specifically represses the transcription of the CDKN2A gene. Efficiently abrogates E2F1-dependent CDKN2A transactivation/de-repression. Binds to the consensus sequence 5'-[GA][CA]GACCCCCCCCC-3'., similarity:Contains 1 BTB (POZ) domain., similarity:Contains 4 C2H2-type zinc fingers., subunit:Interacts with BCL6., tissue specificity:Widely expressed. In normal thymus, expressed in medullary epithelial cells and Hassle's corpuscles (at protein level) . In tonsil, expressed in squamous epithelium and germinal center lymphocytes (at protein level) . Up-regulated in a subset of lymphomas, as well as in a subset of breast, lung, colon, prostate and bladder carcinomas (at protein level) .
Description
Function: Plays a key role in the instruction of early lymphoid progenitors to develop into B lineage by repressing T-cell instructive Notch signals (By similarity). Specifically represses the transcription of the CDKN2A gene. Efficiently abrogates E2F1-dependent CDKN2A transactivation/de-repression. Binds to the consensus sequence 5'-[GA][CA]GACCCCCCCCC-3'. similarity: Contains 1 BTB (POZ) domain. similarity: Contains 4 C2H2-type zinc fingers. subunit: Interacts with BCL6. tissue specificity: Widely expressed. In normal thymus, expressed in medullary epithelial cells and Hassle's corpuscles (at protein level). In tonsil, expressed in squamous epithelium and germinal center lymphocytes (at protein level). Up-regulated in a subset of lymphomas, as well as in a subset of breast, lung, colon, prostate and bladder carcinomas (at protein level).
UniProt
O95365
Swiss Prot
O95365
Reactivity
Human; Mouse; Rat
Immunogen
Synthesized peptide derived from part region of human protein
Clonality
Polyclonal
Source
Rabbit
Applications
WB; ELISA
Concentration
1 mg/ml
Dilution
WB 1:500-2000 ELISA 1:5000-20000
Molecular Weight
64kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
64kD
Fragment
IgG
Subcellular Location
Nucleus . Recruited to double-strand break sites of damaged DNA. .
Gene ID (Human)
51341

Related Products

CatalogName
ES4666-01RAB3IP rabbit pAb
ES20751-01Gab1 Rabbit rabbit pAb
ES20703-01JAK2 Rabbit rabbit pAb
ES20758-01ERK1 Rabbit rabbit pAb
ES20830-01ATG14L Rabbit rabbit pAb
ES20829-01ATG4a Rabbit rabbit pAb
ES20658-01NM23A Rabbit rabbit pAb
ES20826-01ATG5 Rabbit rabbit pAb
ES20659-01NBR1 Rabbit rabbit pAb
ES20825-01ATG7 Rabbit rabbit pAb

Alternative Products

CatalogName
E28PN2982ZBT7A Rabbit Polyclonal Antibody
PAV4420Rabbit Anti-ZBT7A/ZBTB7A Polyclonal Antibody
543880-01ZBT7A discontinued
C47230-01ZBT7A Antibody
MBS8532340-01ZBT7A Polyclonal Antibody
STJ193086Anti-ZBT7A antibody
E106546Human ZBT7A ELISA Kit
WP3349-01U-Blot® ZBT7A Polyclonal Antibody
353130ZBTB7A (Zinc Finger and BTB Domain-Containing Protein 7A, FBI 1, FBI1, FBI-1, Pokemon, TIP21, ZBT7A, ZBTB7, Zinc Finger Protein 857A, ZNF857A)
RTR015Rabbit-to-Rabbit Blocking Reagent

Popular Products