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KLOT rabbit pAb

CAT: 0855-ES11915-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0855-ES11915-01Size:50 µL
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Background
This gene encodes a type-I membrane protein that is related to beta-glucosidases. Reduced production of this protein has been observed in patients with chronic renal failure (CRF), and this may be one of the factors underlying the degenerative processes (e.g., arteriosclerosis, osteoporosis, and skin atrophy) seen in CRF. Also, mutations within this protein have been associated with ageing and bone loss. [provided by RefSeq, Jul 2008]
Description
This gene encodes a type-I membrane protein that is related to beta-glucosidases. Reduced production of this protein has been observed in patients with chronic renal failure (CRF), and this may be one of the factors underlying the degenerative processes (e. g. arteriosclerosis, osteoporosis, and skin atrophy) seen in CRF. Also, mutations within this protein have been associated with ageing and bone loss. [provided by RefSeq, Jul 2008],
UniProt
Q9UEF7
Swiss Prot
Q9UEF7
Reactivity
Human; Mouse; Rat
Immunogen
Synthesized peptide derived from part region of human protein AA range: 400-500
Target
KLOT
Clonality
Polyclonal
Source
Rabbit
Applications
WB; ELISA
Concentration
1 mg/ml
Dilution
WB 1:500-2000 ELISA 1:5000-20000
Buffer
-20°C/1 year
Molecular Weight
111kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
111kD
Fragment
IgG
Subcellular Location
[Isoform 1]: Cell membrane ; Single-pass type I membrane protein . Apical cell membrane ; Single-pass type I membrane protein . Isoform 1 shedding leads to a soluble peptide. .; [Isoform 2]: Secreted .; [Klotho peptide]: Secreted .
Gene ID (Human)
9365