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DNMBP rabbit pAb

CAT: 0855-ES11769-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0855-ES11769-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This gene encodes a protein belonging to the guanine nucleotide exchange factor family, and which regulates the configuration of cell junctions. It contains multiple binding sites for dynamin and thus links dynamin to actin regulatory proteins. Polymorphisms in this gene have been linked to Alzheimer's disease in some populations, though there are conflicting reports of such linkages in other populations. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2015]
Description
This gene encodes a protein belonging to the guanine nucleotide exchange factor family, and which regulates the configuration of cell junctions. It contains multiple binding sites for dynamin and thus links dynamin to actin regulatory proteins. Polymorphisms in this gene have been linked to Alzheimer's disease in some populations, though there are conflicting reports of such linkages in other populations. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2015],
UniProt
Q6XZF7
Swiss Prot
Q6XZF7
Reactivity
Human; Rat; Mouse
Immunogen
Synthesized peptide derived from part region of human protein AA range: 940-990
Clonality
Polyclonal
Source
Rabbit
Applications
WB; ELISA
Concentration
1 mg/ml
Dilution
WB 1:500-2000 ELISA 1:5000-20000
Molecular Weight
173kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
173kD
Fragment
IgG
Subcellular Location
Cytoplasm . Golgi apparatus, Golgi stack . Cytoplasm, cytoskeleton . Cell junction, synapse . Cell junction . Localizes to the apical junction, colocalizes with TJP1. .
Gene ID (Human)
23268

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