CASS4 rabbit pAb

• Background :

  Alternative products:Experimental confirmation may be lacking for some isoforms, function:Possible docking protein which may play a role for tyrosine-kinase-based signaling related to cell adhesion. Regulates FAK activity, focal adhesion integrity, and cell spreading., PTM:Phosphorylated on tyrosines by SRC., similarity:Belongs to the CAS family., similarity:Contains 1 SH3 domain., subunit:Interacts (via SH3 domain) with focal adhesion kinase (via C-terminus) ., tissue specificity:Expressed abundantly in lung and spleen. Also highly expressed in ovarian and leukemia cell lines.

• Description :

  Alternative products: Experimental confirmation may be lacking for some isoforms, function: Possible docking protein which may play a role for tyrosine-kinase-based signaling related to cell adhesion. Regulates FAK activity, focal adhesion integrity, and cell spreading. PTM: Phosphorylated on tyrosines by SRC. similarity: Belongs to the CAS family. similarity: Contains 1 SH3 domain. subunit: Interacts (via SH3 domain) with focal adhesion kinase (via C-terminus). tissue specificity: Expressed abundantly in lung and spleen. Also highly expressed in ovarian and leukemia cell lines.

• UniProt :

  Q9NQ75

• Swiss Prot :

  Q9NQ75

• Reactivity :

  Human; Rat; Mouse

• Immunogen :

  Synthesized peptide derived from part region of human protein AA range: 302-352

• Clonality :

  Polyclonal

• Source :

  Rabbit

• Applications :

  WB; ELISA

• Concentration :

  1 mg/ml

• Dilution :

  WB 1:500-2000 ELISA 1:5000-20000

• Molecular Weight :

  86kD

• Storage Conditions :

  -20°C/1 year

• Observed Molecular Weight :

  86kD

• Fragment :

  IgG

• Subcellular Location :

  Cytoplasm, cytoskeleton . Cell junction, focal adhesion .

• Gene ID (Human) :

  57091