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NPY6R rabbit pAb

CAT: 0855-ES11735-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0855-ES11735-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Caution:Could be the product of a pseudogene. According to PubMed:97066888, PubMed:97066971 and PubMed:9013614, the human NPY6R gene is an expressed pseudogene containing a premature stop codon and encoding a non-functional truncated protein missing the last transmembrane domain. A single base pair deletion relative to the mouse ortholog, results in a truncated protein lacking the seventh transmembrane domain., function:When expressed, is unable to bind pancreatic polypeptide (PP), neuropeptide Y (NPY), or peptide YY (PYY), suggesting that either it is functionally inactive or that it may have acquired a pancreatic polypeptide-independent function., similarity:Belongs to the G-protein coupled receptor 1 family., tissue specificity:Expressed in heart, skeletal muscle, gastrointestinal tissues, spleen, brain and adrenal glands.
Description
Caution: Could be the product of a pseudogene. According to PubMed: 97066888, PubMed: 97066971 and PubMed: 9013614, the human NPY6R gene is an expressed pseudogene containing a premature stop codon and encoding a non-functional truncated protein missing the last transmembrane domain. A single base pair deletion relative to the mouse ortholog, results in a truncated protein lacking the seventh transmembrane domain. function: When expressed, is unable to bind pancreatic polypeptide (PP), neuropeptide Y (NPY), or peptide YY (PYY), suggesting that either it is functionally inactive or that it may have acquired a pancreatic polypeptide-independent function. similarity: Belongs to the G-protein coupled receptor 1 family. tissue specificity: Expressed in heart, skeletal muscle, gastrointestinal tissues, spleen, brain and adrenal glands.
UniProt
Q99463
Swiss Prot
Q99463
Reactivity
Human; Mouse
Immunogen
Synthesized peptide derived from human protein . at AA range: 190-270
Target
NPY6R
Clonality
Polyclonal
Source
Rabbit
Applications
WB; ELISA
Concentration
1 mg/ml
Dilution
WB 1:500-2000 ELISA 1:5000-20000
Buffer
-20°C/1 year
Molecular Weight
31kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
31kD
Fragment
IgG
Subcellular Location
Membrane ; Multi-pass membrane protein .

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