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Alginic acid

CAT: 0804-HY-W127758-01Size: 50 gDry Ice: NoHazardous: No
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CAT#:0804-HY-W127758-01Size:50 g
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Alginic acid is a natural polysaccharide, which has been widely concerned and applied due to its excellent water solubility, film formation, biodegradability and biocompatibility. Alginic acid induces oxidative stress-mediated hormone secretion disorder, apoptosis and autophagy in mouse granulosa cells and ovaries. Alginic acid has an inhibitory effect on histamine release. Anti-anaphylactic and anti-inflammatory properties[1][2][3].
CAS Number
9005-32-7
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Apoptosis; Autophagy; Endogenous Metabolite; Histamine Receptor
Type
Natural Products
Related Pathways
Apoptosis; Autophagy; GPCR/G Protein; Immunology/Inflammation; Metabolic Enzyme/Protease; Neuronal Signaling
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Endocrinology; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/alginic-acid.html
Purity
97.0
Solubility
H2O : 3.03 mg/mL (ultrasonic; adjust pH to 12 with 1M NaOH)
Smiles
O=C(O)[C@@H]1[C@@H](OC)[C@H](O)[C@H](O)[C@H](O[C@H]2[C@H](O)[C@H](O)[C@@H](O[C@H]2C(O)=O)OC)O1.[n]
Molecular Weight
546.39
Precautions
H302, H315, H319, H335
References & Citations
[1]Guo X, et al. Structures, properties and application of alginic acid: A review. Int J Biol Macromol. 2020;162:618-628. |[2]Cui J, et al. Alginic acid induces oxidative stress-mediated hormone secretion disorder, apoptosis and autophagy in mouse granulosa cells and ovaries. Toxicology. 2022;467:153099.|[3]Jeong HJ, et al. Alginic acid has anti-anaphylactic effects and inhibits inflammatory cytokine expression via suppression of nuclear factor-kappaB activation. Clin Exp Allergy. 2006;36 (6) :785-794.
Shipping Conditions
Room Temperature
Storage Conditions
Store at room temperature 3 years
Scientific Category
Natural Products
Clinical Information
No Development Reported
Isoform
Human Endogenous Metabolite