MRGRD rabbit pAb

CAT: 0855-ES11508-01Size: 50 µLDry Ice: NoHazardous: No
CAT#:0855-ES11508-01Size:50 µL
Selected
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Background
Function:May regulate nociceptor function and/or development, including the sensation or modulation of pain. Functions as a specific membrane receptor for beta-alanine. Beta-alanine at micromolar doses specifically evoked Ca (2+) influx in cells expressing the receptor. Beta-alanine decreases forskolin-stimulated cAMP production in cells expressing the receptor, suggesting that the receptor couples with G-protein G (q) and G (i) ., similarity:Belongs to the G-protein coupled receptor 1 family. Mas subfamily., subcellular location:Localized at the plasma membrane but internalized into the cytoplasm after treatment with beta-alanine.
Description
Function: May regulate nociceptor function and/or development, including the sensation or modulation of pain. Functions as a specific membrane receptor for beta-alanine. Beta-alanine at micromolar doses specifically evoked Ca (2+) influx in cells expressing the receptor. Beta-alanine decreases forskolin-stimulated cAMP production in cells expressing the receptor, suggesting that the receptor couples with G-protein G (q) and G (i). similarity: Belongs to the G-protein coupled receptor 1 family. Mas subfamily. subcellular location: Localized at the plasma membrane but internalized into the cytoplasm after treatment with beta-alanine.
UniProt
Q8TDS7
Swiss Prot
Q8TDS7
Reactivity
Human; Rat; Mouse
Immunogen
Synthesized peptide derived from part region of human protein
Target
MRGRD
Clonality
Polyclonal
Source
Rabbit
Applications
WB; ELISA
Concentration
1 mg/ml
Dilution
WB 1:500-2000 ELISA 1:5000-20000
Buffer
-20°C/1 year
Molecular Weight
35kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
35kD
Fragment
IgG
Subcellular Location
Cell membrane ; Multi-pass membrane protein . Localized at the plasma membrane but internalized into the cytoplasm after treatment with beta-alanine.
Gene ID (Human)
116512

Popular Products