C5ARL rabbit pAb

• Background:

  This gene encodes a G-protein coupled receptor 1 family member involved in the complement system of the innate immune response. Unlike classical G-protein coupled receptors, the encoded protein does not associate with intracellular G-proteins. It may instead modulate signal transduction through the beta-arrestin pathway, and may alternatively act as a decoy receptor. This gene may be involved in coronary artery disease and in the pathogenesis of sepsis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2012]

• Description:

  This gene encodes a G-protein coupled receptor 1 family member involved in the complement system of the innate immune response. Unlike classical G-protein coupled receptors, the encoded protein does not associate with intracellular G-proteins. It may instead modulate signal transduction through the beta-arrestin pathway, and may alternatively act as a decoy receptor. This gene may be involved in coronary artery disease and in the pathogenesis of sepsis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2012],

• UniProt:

  Q9P296

• Swiss Prot:

  Q9P296

• Reactivity:

  Human; Rat; Mouse

• Immunogen:

  Synthesized peptide derived from human protein . at AA range: 270-350

• Clonality:

  Polyclonal

• Source:

  Rabbit

• Applications:

  WB; ELISA

• Concentration:

  1 mg/ml

• Dilution:

  WB 1:500-2000 ELISA 1:5000-20000

• Molecular Weight:

  37kD

• Storage Conditions:

  -20°C/1 year

• Observed Molecular Weight:

  37kD

• Fragment:

  IgG

• Subcellular Location:

  Cell membrane ; Multi-pass membrane protein .

• Gene ID (Human):

  27202