Products for Research Use Only
RegisterLogin

TIA1 rabbit pAb

CAT: 0855-ES11391-01Size: 50 µLDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0855-ES11391-01Size:50 µL
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Background
The product encoded by this gene is a member of a RNA-binding protein family and possesses nucleolytic activity against cytotoxic lymphocyte (CTL) target cells. It has been suggested that this protein may be involved in the induction of apoptosis as it preferentially recognizes poly (A) homopolymers and induces DNA fragmentation in CTL targets. The major granule-associated species is a 15-kDa protein that is thought to be derived from the carboxyl terminus of the 40-kDa product by proteolytic processing. Alternative splicing resulting in different isoforms of this gene product has been described in the literature. [provided by RefSeq, Jul 2008]
Description
The product encoded by this gene is a member of a RNA-binding protein family and possesses nucleolytic activity against cytotoxic lymphocyte (CTL) target cells. It has been suggested that this protein may be involved in the induction of apoptosis as it preferentially recognizes poly (A) homopolymers and induces DNA fragmentation in CTL targets. The major granule-associated species is a 15-kDa protein that is thought to be derived from the carboxyl terminus of the 40-kDa product by proteolytic processing. Alternative splicing resulting in different isoforms of this gene product has been described in the literature. [provided by RefSeq, Jul 2008],
UniProt
P31483
Swiss Prot
P31483
Reactivity
Human; Mouse
Immunogen
Synthesized peptide derived from human protein . at AA range: 201-250
Target
TIA1
Clonality
Polyclonal
Source
Rabbit
Applications
WB; ELISA
Concentration
1 mg/ml
Dilution
WB 1:500-2000 ELISA 1:5000-20000
Buffer
-20°C/1 year
Molecular Weight
42kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
42kD
Fragment
IgG
Subcellular Location
Nucleus . Cytoplasm . Cytoplasm, Stress granule . Accumulates in cytoplasmic stress granules (SG) following cellular damage (PubMed:15371533, PubMed:10613902) . Recruitment to SG is induced by Zn (2+) (By similarity) . .
Gene ID (Human)
7072

Related Products

CatalogName
ES9226-01TIAF1 rabbit pAb
ES11819-01TIAM1 rabbit pAb
ES4666-01RAB3IP rabbit pAb
ES20751-01Gab1 Rabbit rabbit pAb
ES20703-01JAK2 Rabbit rabbit pAb
ES20758-01ERK1 Rabbit rabbit pAb
ES20830-01ATG14L Rabbit rabbit pAb
ES20829-01ATG4a Rabbit rabbit pAb
ES20658-01NM23A Rabbit rabbit pAb
ES20826-01ATG5 Rabbit rabbit pAb

Alternative Products

CatalogName
APA1842-01TIA1 Rabbit pAb
RDSA67320TIA1 Rabbit mAb
NBP3-14194PERabbit Monoclonal TIA1 Antibody (TIA1/1352R) [PE]
NBP3-14194HRabbit Monoclonal TIA1 Antibody (TIA1/1352R) [HRP]
NBP3-14194FRabbit Monoclonal TIA1 Antibody (TIA1/1352R) [FITC]
NBP3-14194APCRabbit Monoclonal TIA1 Antibody (TIA1/1352R) [Allophycocyanin]

Popular Products