ZFP42 rabbit pAb

CAT: 0855-ES11363-01Size: 50 µLDry Ice: NoHazardous: No

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CAT#:0855-ES11363-01Size:50 µL

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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Background

Function:Involved in self-renewal property of ES cells (By similarity) . May be involved in transcriptional regulation., induction:Down-regulation upon retinoic acid addition to F9 stem cells., similarity:Belongs to the krueppel C2H2-type zinc-finger protein family., similarity:Contains 4 C2H2-type zinc fingers., tissue specificity:Expressed in kidney, epidermal keratinocytes, prostate epithelial cells, bronchial and small airway lung epithelial cells (at protein level) . Expressed in malignant kidney and several carcinoma cell lines (at protein level) . Expressed in embryonic stem cells, kidney, epidermal keratinocytes, prostate epithelial cells, bronchial and small airway lung epithelial cells. Expressed in embryonal carcinomas, seminomas, malignant kidney and several carcinoma cell lines.

Description

Function: Involved in self-renewal property of ES cells (By similarity). May be involved in transcriptional regulation. induction: Down-regulation upon retinoic acid addition to F9 stem cells. similarity: Belongs to the krueppel C2H2-type zinc-finger protein family. similarity: Contains 4 C2H2-type zinc fingers. tissue specificity: Expressed in kidney, epidermal keratinocytes, prostate epithelial cells, bronchial and small airway lung epithelial cells (at protein level). Expressed in malignant kidney and several carcinoma cell lines (at protein level). Expressed in embryonic stem cells, kidney, epidermal keratinocytes, prostate epithelial cells, bronchial and small airway lung epithelial cells. Expressed in embryonal carcinomas, seminomas, malignant kidney and several carcinoma cell lines.

UniProt

Q96MM3

Swiss Prot

Q96MM3

Reactivity

Human; Mouse

Immunogen

Synthesized peptide derived from human protein . at AA range: 70-150

Target

ZFP42

Clonality

Polyclonal

Source

Rabbit

Applications

WB; ELISA

Concentration

1 mg/ml

Dilution

WB 1:500-2000 ELISA 1:5000-20000

Buffer

-20°C/1 year

Molecular Weight

34kD

Storage Conditions

-20°C/1 year

Observed Molecular Weight

34kD

Fragment

IgG

Subcellular Location

Nucleus .

Gene ID (Human)

132625

UniProtKB · Q96MM3

Zinc finger protein 42 homolog

ZFP42_HUMAN · Homo sapiens

View on UniProt ↗

Primary accession: Q96MM3
Review status: UniProtKB reviewed (Swiss-Prot)
Gene: ZFP42
Protein existence: 1: Evidence at protein level
Organism: Homo sapiens (Human)
Taxonomy ID: 9606
Alternative names: Zfp-42
EC number: —
Processing: —
Secondary accessions: D3DP65, Q8WXE2

Protein keywords

Molecular function

ActivatorDNA-binding

PTM

Isopeptide bondUbl conjugation

Ligand

Metal-bindingZinc

Cellular component

Nucleus

Technical term

Proteomics identificationReference proteome

Domain

RepeatZinc-finger

Biological process

TranscriptionTranscription regulation

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