B2MG rabbit pAb

• Background :

  This gene encodes a serum protein found in association with the major histocompatibility complex (MHC) class I heavy chain on the surface of nearly all nucleated cells. The protein has a predominantly beta-pleated sheet structure that can form amyloid fibrils in some pathological conditions. The encoded antimicrobial protein displays antibacterial activity in amniotic fluid. A mutation in this gene has been shown to result in hypercatabolic hypoproteinemia.[provided by RefSeq, Aug 2014]

• Description :

  This gene encodes a serum protein found in association with the major histocompatibility complex (MHC) class I heavy chain on the surface of nearly all nucleated cells. The protein has a predominantly beta-pleated sheet structure that can form amyloid fibrils in some pathological conditions. The encoded antimicrobial protein displays antibacterial activity in amniotic fluid. A mutation in this gene has been shown to result in hypercatabolic hypoproteinemia. [provided by RefSeq, Aug 2014],

• UniProt :

  P61769

• Swiss Prot :

  P61769

• Reactivity :

  Human; Rat; Mouse

• Immunogen :

  Synthesized peptide derived from human protein . at AA range: 40-120

• Clonality :

  Polyclonal

• Source :

  Rabbit

• Applications :

  WB; ELISA

• Concentration :

  1 mg/ml

• Dilution :

  WB 1:500-2000 ELISA 1:5000-20000

• Molecular Weight :

  13kD

• Storage Conditions :

  -20°C/1 year

• Observed Molecular Weight :

  13kD

• Fragment :

  IgG

• Subcellular Location :

  Secreted . Cell surface . Detected in serum and urine (PubMed:1336137, PubMed:7554280) . .; (Microbial infection) In the presence of M.tuberculosis EsxA-EsxB complex decreased amounts of B2M are found on the cell surface (PubMed:25356553) . .

• Gene ID (Human) :

  567