B2MG rabbit pAb

CAT: 0855-ES11333-01Size: 50 µLDry Ice: NoHazardous: No
CAT#:0855-ES11333-01Size:50 µL
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Background
This gene encodes a serum protein found in association with the major histocompatibility complex (MHC) class I heavy chain on the surface of nearly all nucleated cells. The protein has a predominantly beta-pleated sheet structure that can form amyloid fibrils in some pathological conditions. The encoded antimicrobial protein displays antibacterial activity in amniotic fluid. A mutation in this gene has been shown to result in hypercatabolic hypoproteinemia.[provided by RefSeq, Aug 2014]
Description
This gene encodes a serum protein found in association with the major histocompatibility complex (MHC) class I heavy chain on the surface of nearly all nucleated cells. The protein has a predominantly beta-pleated sheet structure that can form amyloid fibrils in some pathological conditions. The encoded antimicrobial protein displays antibacterial activity in amniotic fluid. A mutation in this gene has been shown to result in hypercatabolic hypoproteinemia. [provided by RefSeq, Aug 2014],
UniProt
P61769
Swiss Prot
P61769
Reactivity
Human; Rat; Mouse
Immunogen
Synthesized peptide derived from human protein . at AA range: 40-120
Target
B2MG
Clonality
Polyclonal
Source
Rabbit
Applications
WB; ELISA
Concentration
1 mg/ml
Dilution
WB 1:500-2000 ELISA 1:5000-20000
Buffer
-20°C/1 year
Molecular Weight
13kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
13kD
Fragment
IgG
Subcellular Location
Secreted . Cell surface . Detected in serum and urine (PubMed:1336137, PubMed:7554280) . .; (Microbial infection) In the presence of M.tuberculosis EsxA-EsxB complex decreased amounts of B2M are found on the cell surface (PubMed:25356553) . .
Gene ID (Human)
567

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