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NADL2 rabbit pAb

CAT: 0855-ES11263-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0855-ES11263-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Caution:Although related to the peptidase M28 family, it is probably inactive as an hydrolase due to lack of the conserved zinc-binding and active sites., function:May be catalytically inactive., miscellaneous:The gene maps to 3q26.31, a region associated with Cornelia de Lange syndrome. However, PubMed:15168106 failed to identify specific mutations in a panel of DNA samples from patients with Cornelia de Lange syndrome., sequence caution:Contaminating sequence at the C-terminus., similarity:Belongs to the peptidase M28 family. M28B subfamily., tissue specificity:Expressed at higher level in kidney and placenta. In embryo, it is mainly confined to duodenal and stomach endoderm, mesonephros, metanephros and pancreas.
Description
Caution: Although related to the peptidase M28 family, it is probably inactive as an hydrolase due to lack of the conserved zinc-binding and active sites. function: May be catalytically inactive. miscellaneous: The gene maps to 3q26. 31, a region associated with Cornelia de Lange syndrome. However, PubMed: 15168106 failed to identify specific mutations in a panel of DNA samples from patients with Cornelia de Lange syndrome. sequence Caution: Contaminating sequence at the C-terminus. similarity: Belongs to the peptidase M28 family. M28B subfamily. tissue specificity: Expressed at higher level in kidney and placenta. In embryo, it is mainly confined to duodenal and stomach endoderm, mesonephros, metanephros and pancreas.
UniProt
Q58DX5
Swiss Prot
Q58DX5
Reactivity
Human; Rat; Mouse
Immunogen
Synthesized peptide derived from human protein . at AA range: 190-270
Clonality
Polyclonal
Source
Rabbit
Applications
WB; ELISA
Concentration
1 mg/ml
Dilution
WB 1:500-2000 ELISA 1:5000-20000
Molecular Weight
87kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
87kD
Fragment
IgG
Subcellular Location
Membrane ; Single-pass type II membrane protein .
Gene ID (Human)
254827

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