LY86 rabbit pAb

• Background:

  Function:May cooperate with CD180 and TLR4 to mediate the innate immune response to bacterial lipopolysaccharide (LPS) and cytokine production. Important for efficient CD180 cell surface expression., induction:In monocytes, down-regulated by the cell-wall fraction of Mycobacterium bovis (BCG-CWS) ., subcellular location:Associated with CD180 at the cell surface., subunit:Binds CD180., tissue specificity:Highly expressed in B-cells, monocytes and tonsil.

• Description:

  Function: May cooperate with CD180 and TLR4 to mediate the innate immune response to bacterial lipopolysaccharide (LPS) and Cytokine production. Important for efficient CD180 cell surface expression. induction: In monocytes, down-regulated by the cell-wall fraction of Mycobacterium bovis (BCG-CWS). subcellular location: Associated with CD180 at the cell surface. subunit: Binds CD180. tissue specificity: Highly expressed in B-cells, monocytes and tonsil.

• UniProt:

  O95711

• Swiss Prot:

  O95711

• Reactivity:

  Human; Mouse

• Immunogen:

  Synthesized peptide derived from human protein . at AA range: 80-160

• Clonality:

  Polyclonal

• Source:

  Rabbit

• Applications:

  WB; ELISA

• Concentration:

  1 mg/ml

• Dilution:

  WB 1:500-2000 ELISA 1:5000-20000

• Molecular Weight:

  17kD

• Storage Conditions:

  -20°C/1 year

• Observed Molecular Weight:

  17kD

• Fragment:

  IgG

• Subcellular Location:

  Secreted, extracellular space. Associated with CD180 at the cell surface.

• Gene ID (Human):

  9450