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BGH3 rabbit pAb

CAT: 0855-ES11167-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0855-ES11167-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This gene encodes an RGD-containing protein that binds to type I, II and IV collagens. The RGD motif is found in many extracellular matrix proteins modulating cell adhesion and serves as a ligand recognition sequence for several integrins. This protein plays a role in cell-collagen interactions and may be involved in endochondrial bone formation in cartilage. The protein is induced by transforming growth factor-beta and acts to inhibit cell adhesion. Mutations in this gene are associated with multiple types of corneal dystrophy. [provided by RefSeq, Jul 2008]
Description
This gene encodes an RGD-containing protein that binds to type I, II and IV collagens. The RGD motif is found in many extracellular matrix proteins modulating cell adhesion and serves as a ligand recognition sequence for several integrins. This protein plays a role in cell-collagen interactions and may be involved in endochondrial bone formation in cartilage. The protein is induced by transforming growth factor-beta and acts to inhibit cell adhesion. Mutations in this gene are associated with multiple types of corneal dystrophy. [provided by RefSeq, Jul 2008],
UniProt
Q15582
Swiss Prot
Q15582
Reactivity
Human; Mouse
Immunogen
Synthesized peptide derived from human protein . at AA range: 230-310
Clonality
Polyclonal
Source
Rabbit
Applications
WB; ELISA
Concentration
1 mg/ml
Dilution
WB 1:500-2000 ELISA 1:5000-20000
Molecular Weight
75kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
75kD
Fragment
IgG
Subcellular Location
Secreted . Secreted, extracellular space, extracellular matrix . May be associated both with microfibrils and with the cell surface (PubMed:8077289) . .
Gene ID (Human)
7045

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