CILP1 rabbit pAb

CAT: 0855-ES10913-01Size: 50 µLDry Ice: NoHazardous: No
CAT#:0855-ES10913-01Size:50 µL
Selected
PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Background
Major alterations in the composition of the cartilage extracellular matrix occur in joint disease, such as osteoarthrosis. This gene encodes the cartilage intermediate layer protein (CILP), which increases in early osteoarthrosis cartilage. The encoded protein was thought to encode a protein precursor for two different proteins; an N-terminal CILP and a C-terminal homolog of NTPPHase, however, later studies identified no nucleotide pyrophosphatase phosphodiesterase (NPP) activity. The full-length and the N-terminal domain of this protein was shown to function as an IGF-1 antagonist. An allelic variant of this gene has been associated with lumbar disc disease. [provided by RefSeq, Sep 2010]
Description
Major alterations in the composition of the cartilage extracellular matrix occur in joint disease, such as osteoarthrosis. This gene encodes the cartilage intermediate layer protein (CILP), which increases in early osteoarthrosis cartilage. The encoded protein was thought to encode a protein precursor for two different proteins; an N-terminal CILP and a C-terminal homolog of NTPPHase, however, later studies identified no nucleotide pyrophosphatase phosphodiesterase (NPP) activity. The full-length and the N-terminal domain of this protein was shown to function as an IGF-1 antagonist. An allelic variant of this gene has been associated with lumbar disc disease. [provided by RefSeq, Sep 2010],
UniProt
O75339
Swiss Prot
O75339
Reactivity
Human; Rat; Mouse
Immunogen
Synthesized peptide derived from part region of human protein
Clonality
Polyclonal
Source
Rabbit
Applications
WB; ELISA
Concentration
1 mg/ml
Dilution
WB 1:500-2000 ELISA 1:5000-20000
Molecular Weight
130kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
130kD
Fragment
IgG
Subcellular Location
Secreted, extracellular space, extracellular matrix .
Gene ID (Human)
8483

Related Products

CatalogName
ES4666-01RAB3IP rabbit pAb
ES20751-01Gab1 Rabbit rabbit pAb
ES20703-01JAK2 Rabbit rabbit pAb
ES20758-01ERK1 Rabbit rabbit pAb
ES20599-01VEGF Rabbit rabbit pAb
ES20825-01ATG7 Rabbit rabbit pAb
ES20596-01WIPI2 Rabbit rabbit pAb
ES20659-01NBR1 Rabbit rabbit pAb
ES20831-01ATG13 Rabbit rabbit pAb
ES20658-01NM23A Rabbit rabbit pAb

Alternative Products

CatalogName
E28PN1967CILP1 Rabbit Polyclonal Antibody
PAV860Rabbit Anti-CILP1/CILP Polyclonal Antibody
MBS9521014-01CILP1 Antibody
534732-01CILP1 discontinued
MBS8531321-01CILP1 Polyclonal Antibody
A06239Anti-CILP1 Antibody
E101956Pig CILP1 ELISA Kit
E101954Human CILP1 ELISA Kit
E101955Mouse CILP1 ELISA Kit
YP-W100674-01Human Cartilage intermediate layer protein 1 (CILP1) ELISA Kit

Popular Products