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MUL1 rabbit pAb

CAT: 0855-ES10762-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0855-ES10762-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Domain:The zinc finger domain is required for E3 ligase activity., function:E3 ubiquitin-protein ligase that plays a role in the control of mitochondrial morphology. Promotes mitochondrial fragmentation and influences mitochondrial localization. Inhibits cell growth. When overexpressed, activates JNK through MAP3K7/TAK1 and induces caspase-dependent apoptosis. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfer the ubiquitin to targeted substrates., pathway:Protein modification; protein ubiquitination., similarity:Contains 1 RING-type zinc finger., subcellular location:Transported in mitochondrion-derived vesicles from the mitochondrion to the peroxisome., subunit:Homooligomer. Interacts with MAP3K7/TAK1., tissue specificity:Widely expressed with highest levels in the heart, skeletal muscle, placenta, kidney and liver. Barely detectable in colon and thymus.
Description
Domain: The zinc finger domain is required for E3 ligase activity. function: E3 ubiquitin-protein ligase that plays a role in the control of mitochondrial morphology. Promotes mitochondrial fragmentation and influences mitochondrial localization. Inhibits cell growth. When overexpressed, activates JNK through MAP3K7/TAK1 and induces caspase-dependent apoptosis. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfer the ubiquitin to targeted substrates. pathway: Protein modification; protein ubiquitination. similarity: Contains 1 RING-type zinc finger. subcellular location: Transported in mitochondrion-derived vesicles from the mitochondrion to the peroxisome. subunit: Homooligomer. Interacts with MAP3K7/TAK1. tissue specificity: Widely expressed with highest levels in the heart, skeletal muscle, placenta, kidney and liver. Barely detectable in colon and thymus.
UniProt
Q969V5
Swiss Prot
Q969V5
Reactivity
Human; Mouse
Immunogen
Synthesized peptide derived from part region of human protein
Target
MUL1
Clonality
Polyclonal
Source
Rabbit
Applications
WB; ELISA
Concentration
1 mg/ml
Dilution
WB 1:500-2000 ELISA 1:5000-20000
Buffer
-20°C/1 year
Molecular Weight
38kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
38kD
Fragment
IgG
Subcellular Location
Mitochondrion outer membrane ; Multi-pass membrane protein . Peroxisome . Transported in mitochondrion-derived vesicles from the mitochondrion to the peroxisome. .
Gene ID (Human)
79594

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