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MARE2 rabbit pAb

CAT: 0855-ES10751-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0855-ES10751-01Size:50 µL
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Background
The protein encoded by this gene shares significant homology to the adenomatous polyposis coli (APC) protein-binding EB1 gene family. This protein is a microtubule-associated protein that is necessary for spindle symmetry during mitosis. It is thought to play a role in the tumorigenesis of colorectal cancers and the proliferative control of normal cells. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Jan 2012]
Description
The protein encoded by this gene shares significant homology to the adenomatous polyposis coli (APC) protein-binding EB1 gene family. This protein is a microtubule-associated protein that is necessary for spindle symmetry during mitosis. It is thought to play a role in the tumorigenesis of colorectal cancers and the proliferative control of normal cells. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Jan 2012],
UniProt
Q15555
Swiss Prot
Q15555
Reactivity
Human; Mouse; Rat
Immunogen
Synthesized peptide derived from part region of human protein
Target
MARE2
Clonality
Polyclonal
Source
Rabbit
Applications
WB; ELISA
Concentration
1 mg/ml
Dilution
WB 1:500-2000 ELISA 1:5000-20000
Buffer
-20°C/1 year
Molecular Weight
35kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
35kD
Fragment
IgG
Subcellular Location
Cytoplasm, cytoskeleton . Associated with the microtubule network. Accumulates at the plus end of microtubules.
Gene ID (Human)
10982

UniProtKB · Q15555

Microtubule-associated protein RP/EB family member 2

MARE2_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q15555
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
MAPRE2
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
—
Secondary accessions
B2RE21, B3KR39, B4DJV4, B7Z2L3, E9PHR3, F5H1V8, G5E9I6, Q9UQ33
Protein keywords

PTM

AcetylationPhosphoproteinUbl conjugation

Coding sequence diversity

Alternative splicing

Biological process

Cell cycleCell divisionMitosis

Cellular component

CytoplasmCytoskeletonMicrotubule

Technical term

Proteomics identificationReference proteome