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T22D3 rabbit pAb

CAT: 0855-ES10634-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0855-ES10634-01Size:50 µL
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Background
This gene encodes the anti-inflammatory protein glucocorticoid (GC) -induced leucine zipper. Expression of this gene stimulated by glucocorticoids and interleukin 10 and it appears to play a key role in the anti-inflammatory and immunosuppressive effects of this steroid. This protein has also been shown to inhibit pro-inflammatory molecules including nuclear factor κB. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jan 2016]
Description
This gene encodes the anti-inflammatory protein glucocorticoid (GC)-induced leucine zipper. Expression of this gene stimulated by glucocorticoids and interleukin 10 and it appears to play a key role in the anti-inflammatory and immunosuppressive effects of this steroid. This protein has also been shown to inhibit pro-inflammatory molecules including nuclear factor κB. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jan 2016],
UniProt
Q99576
Swiss Prot
Q99576
Reactivity
Human; Rat; Mouse
Immunogen
Synthesized peptide derived from part region of human protein
Target
T22D3
Clonality
Polyclonal
Source
Rabbit
Applications
WB; ELISA
Concentration
1 mg/ml
Dilution
WB 1:500-2000 ELISA 1:5000-20000
Buffer
-20°C/1 year
Molecular Weight
14kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
14kD
Fragment
IgG
Subcellular Location
[Isoform 1]: Cytoplasm . Nucleus . Localization depends on differentiation status of myoblasts. In undifferentiated myoblasts, isoform 1 localizes to the cytoplasm, but in differentiating myoblasts, isoform 1 is localized to the nucleus (By similarity) . .
Gene ID (Human)
1831

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