AP2D rabbit pAb

CAT: 0855-ES10596-01Size: 50 µLDry Ice: NoHazardous: No
CAT#:0855-ES10596-01Size:50 µL
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Background
Function:Sequence-specific DNA-binding protein that interacts with inducible viral and cellular enhancer elements to regulate transcription of selected genes. AP-2 factors bind to the consensus sequence 5'-GCCNNNGGC-3' and activate genes involved in a large spectrum of important biological functions including proper eye, face, body wall, limb and neural tube development. They also suppress a number of genes including MCAM/MUC18, C/EBP alpha and MYC., online information:Activatin protein 2 entry, similarity:Belongs to the AP-2 family., subunit:Binds DNA as a dimer. Can form homodimers or heterodimers with other AP-2 family members., tissue specificity:Highly expressed in brain, placenta, skeletal muscle, thymus, small intestine, and prostate, and expressed at lower levels in leukocyte, spleen, testis, ovary and colon. Barely detectable in heart, kidney, liver, lung or pancreas.
Description
Function: Sequence-specific DNA-binding protein that interacts with inducible viral and cellular enhancer elements to regulate transcription of selected genes. AP-2 factors bind to the consensus sequence 5'-GCCNNNGGC-3' and activate genes involved in a large spectrum of important biological functions including proper eye, face, body wall, limb and neural tube development. They also suppress a number of genes including MCAM/MUC18, C/EBP alpha and MYC. online information: Activatin protein 2 entry, similarity: Belongs to the AP-2 family. subunit: Binds DNA as a dimer. Can form homodimers or heterodimers with other AP-2 family members. tissue specificity: Highly expressed in brain, placenta, skeletal muscle, thymus, small intestine, and prostate, and expressed at lower levels in leukocyte, spleen, testis, ovary and colon. Barely detectable in heart, kidney, liver, lung or pancreas.
UniProt
Q7Z6R9
Swiss Prot
Q7Z6R9
Reactivity
Human; Mouse
Immunogen
Synthesized peptide derived from human protein . at AA range: 280-360
Clonality
Polyclonal
Source
Rabbit
Applications
WB; ELISA
Concentration
1 mg/ml
Dilution
WB 1:500-2000 ELISA 1:5000-20000
Molecular Weight
49kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
49kD
Fragment
IgG
Subcellular Location
Nucleus .
Gene ID (Human)
83741

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