AP2B rabbit pAb
CAT:
855-ES18310-01
Size:
50 μL
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
AP2B rabbit pAb
- Description: This gene encodes a member of the AP-2 family of transcription factors. AP-2 proteins form homo- or hetero-dimers with other AP-2 family members and bind specific DNA sequences. They are thought to stimulate cell proliferation and suppress terminal differentiation of specific cell types during embryonic development. Specific AP-2 family members differ in their expression patterns and binding affinity for different promoters. This protein functions as both a transcriptional activator and repressor. Mutations in this gene result in autosomal dominant Char syndrome, suggesting that this gene functions in the differentiation of neural crest cell derivatives. [provided by RefSeq, Jul 2008],
- Gene ID: 7021
- UniProt: Q92481
- Cellular Locus: Nucleus. In the brain, localizes to the arcuate hypothalamic nucleus, the ventromedial hypothalamic nucleus and the accumbens nucleus of the ventral striatum..
- Host: Rabbit
- Species Reactivity: Human, Mouse
- Immunogen: Synthesized peptide derived from human AP2B AA range: 18-68
- Clonality: Polyclonal
- Validated Applications: WB
- Stability: 1 year
- Concentration: 1 mg/mL
- Dilution: WB 1：500-2000
- Storage Conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.