CUL7 rabbit pAb

CAT: 0855-ES10534-01Size: 50 µLDry Ice: NoHazardous: No
CAT#:0855-ES10534-01Size:50 µL
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Background
The protein encoded by this gene is a component of an E3 ubiquitin-protein ligase complex. The encoded protein interacts with TP53, CUL9, and FBXW8 proteins. Defects in this gene are a cause of 3M syndrome type 1 (3M1) . Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2009]
Description
The protein encoded by this gene is a component of an E3 ubiquitin-protein ligase complex. The encoded protein interacts with TP53, CUL9, and FBXW8 proteins. Defects in this gene are a cause of 3M syndrome type 1 (3M1). Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2009],
UniProt
Q14999
Swiss Prot
Q14999
Reactivity
Human; Mouse
Immunogen
Synthesized peptide derived from human protein . at AA range: 1570-1650
Clonality
Polyclonal
Source
Rabbit
Applications
WB; ELISA
Concentration
1 mg/ml
Dilution
WB 1:500-2000 ELISA 1:5000-20000
Molecular Weight
186kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
186kD
Fragment
IgG
Subcellular Location
Cytoplasm. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, perinuclear region. Golgi apparatus. Colocalizes with FBXW8 at the Golgi apparatus in neurons; localization to Golgi is mediated by OBSL1. During mitosis, localizes to the mitotic apparatus (PubMed:24793695) . CCDC8 is required for centrosomal location (PubMed:24793695) . .
Gene ID (Human)
9820

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