UIMC1 rabbit pAb

• Background:

  Ubiquitin interaction motif containing 1 (UIMC1) Homo sapiens This gene encodes a nuclear protein that interacts with Brca1 (breast cancer 1) in a complex to recognize and repair DNA lesions. This protein binds ubiquitinated lysine 63 of histone H2A and H2AX. This protein may also function as a repressor of transcription. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2015]

• Description:

  Ubiquitin interaction motif containing 1 (UIMC1) Homo sapiens This gene encodes a nuclear protein that interacts with Brca1 (breast cancer 1) in a complex to recognize and repair DNA lesions. This protein binds ubiquitinated lysine 63 of histone H2A and H2AX. This protein may also function as a repressor of transcription. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2015],

• UniProt:

  Q96RL1

• Swiss Prot:

  Q96RL1

• Reactivity:

  Human; Rat; Mouse

• Immunogen:

  Synthesized peptide derived from part region of human protein

• Clonality:

  Polyclonal

• Source:

  Rabbit

• Applications:

  WB; ELISA

• Concentration:

  1 mg/ml

• Dilution:

  WB 1:500-2000 ELISA 1:5000-20000

• Molecular Weight:

  79kD

• Storage Conditions:

  -20°C/1 year

• Observed Molecular Weight:

  79kD

• Fragment:

  IgG

• Subcellular Location:

  Nucleus . Localizes at sites of DNA damage at double-strand breaks (DSBs) .

• Gene ID (Human):

  51720