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UIMC1 rabbit pAb

CAT: 0855-ES10427-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0855-ES10427-01Size:50 µL
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Background
Ubiquitin interaction motif containing 1 (UIMC1) Homo sapiens This gene encodes a nuclear protein that interacts with Brca1 (breast cancer 1) in a complex to recognize and repair DNA lesions. This protein binds ubiquitinated lysine 63 of histone H2A and H2AX. This protein may also function as a repressor of transcription. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2015]
Description
Ubiquitin interaction motif containing 1 (UIMC1) Homo sapiens This gene encodes a nuclear protein that interacts with Brca1 (breast cancer 1) in a complex to recognize and repair DNA lesions. This protein binds ubiquitinated lysine 63 of histone H2A and H2AX. This protein may also function as a repressor of transcription. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2015],
UniProt
Q96RL1
Swiss Prot
Q96RL1
Reactivity
Human; Rat; Mouse
Immunogen
Synthesized peptide derived from part region of human protein
Clonality
Polyclonal
Source
Rabbit
Applications
WB; ELISA
Concentration
1 mg/ml
Dilution
WB 1:500-2000 ELISA 1:5000-20000
Molecular Weight
79kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
79kD
Fragment
IgG
Subcellular Location
Nucleus . Localizes at sites of DNA damage at double-strand breaks (DSBs) .
Gene ID (Human)
51720

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