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SCAR5 rabbit pAb

CAT: 0855-ES10194-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0855-ES10194-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Function:Ferritin receptor that mediates non-transferrin-dependent delivery of iron. Mediates cellular uptake of ferritin-bound iron by stimulating ferritin endocytosis from the cell surface with consequent iron delivery within the cell. Delivery of iron to cells by ferritin is required for the development of specific cell types, suggesting the existence of cell type-specific mechanisms of iron traffic in organogenesis, which alternatively utilize transferrin or non-transferrin iron delivery pathways. Ferritin mediates iron uptake in capsule cells of the developing kidney. Binds preferrentially ferritin light chain (FTL) compared to heavy chain (FTH1) ., similarity:Belongs to the SCARA5 family., similarity:Contains 1 collagen-like domain., similarity:Contains 1 SRCR domain., subunit:Homotrimer.
Description
Function: Ferritin receptor that mediates non-transferrin-dependent delivery of iron. Mediates cellular uptake of ferritin-bound iron by stimulating ferritin endocytosis from the cell surface with consequent iron delivery within the cell. Delivery of iron to cells by ferritin is required for the development of specific cell types, suggesting the existence of cell type-specific mechanisms of iron traffic in organogenesis, which alternatively utilize transferrin or non-transferrin iron delivery pathways. Ferritin mediates iron uptake in capsule cells of the developing kidney. Binds preferrentially ferritin light chain (FTL) compared to heavy chain (FTH1). similarity: Belongs to the SCARA5 family. similarity: Contains 1 collagen-like domain. similarity: Contains 1 SRCR domain. subunit: Homotrimer.
UniProt
Q6ZMJ2
Swiss Prot
Q6ZMJ2
Reactivity
Human; Mouse
Immunogen
Synthesized peptide derived from human protein . at AA range: 230-310
Clonality
Polyclonal
Source
Rabbit
Applications
WB; ELISA
Concentration
1 mg/ml
Dilution
WB 1:500-2000 ELISA 1:5000-20000
Molecular Weight
54kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
54kD
Fragment
IgG
Subcellular Location
Cell membrane ; Single-pass type II membrane protein .
Gene ID (Human)
286133

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