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PPR1A rabbit pAb

CAT: 0855-ES10055-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0855-ES10055-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Function:Inhibitor of protein-phosphatase 1. This protein may be important in hormonal control of glycogen metabolism. Hormones that elevate intracellular cAMP increase I-1 activity in many tissues. I-1 activation may impose cAMP control over proteins that are not directly phosphorylated by PKA. Following a rise in intracellular calcium, I-1 is inactivated by calcineurin (or PP2B) . Does not inhibit type-2 phosphatases., PTM:Phosphorylation of Thr-35 is required for activity., similarity:Belongs to the protein phosphatase inhibitor 1 family., subunit:Interacts with PPP1R15A.
Description
Function: Inhibitor of protein-phosphatase 1. This protein may be important in hormonal control of glycogen metabolism. Hormones that elevate intracellular cAMP increase I-1 activity in many tissues. I-1 activation may impose cAMP control over proteins that are not directly phosphorylated by PKA. Following a rise in intracellular calcium, I-1 is inactivated by calcineurin (or PP2B). Does not inhibit type-2 phosphatases. PTM: Phosphorylation of Thr-35 is required for activity. similarity: Belongs to the protein phosphatase inhibitor 1 family. subunit: Interacts with PPP1R15A.
UniProt
Q13522
Swiss Prot
Q13522
Reactivity
Human; Mouse; Rat
Immunogen
Synthesized peptide derived from human protein . at AA range: 40-120
Target
PPR1A
Clonality
Polyclonal
Source
Rabbit
Applications
WB; ELISA
Concentration
1 mg/ml
Dilution
WB 1:500-2000 ELISA 1:5000-20000
Buffer
-20°C/1 year
Molecular Weight
18kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
18kD
Fragment
IgG
Subcellular Location
Extracellular space, cytoplasm
Gene ID (Human)
5502

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