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MYO1A rabbit pAb

CAT: 0855-ES9849-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0855-ES9849-01Size:50 µL
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Background
This gene encodes a member of the myosin superfamily. The protein represents an unconventional myosin; it should not be confused with the conventional skeletal muscle myosin-1 (MYH1) . Unconventional myosins contain the basic domains characteristic of conventional myosins and are further distinguished from class members by their tail domains. They function as actin-based molecular motors. Mutations in this gene have been associated with autosomal dominant deafness. Alternatively spliced variants have been found for this gene. [provided by RefSeq, Dec 2011]
Description
This gene encodes a member of the myosin superfamily. The protein represents an unconventional myosin; it should not be confused with the conventional skeletal muscle myosin-1 (MYH1). Unconventional myosins contain the basic domains characteristic of conventional myosins and are further distinguished from class members by their tail domains. They function as actin-based molecular motors. Mutations in this gene have been associated with autosomal dominant deafness. Alternatively spliced variants have been found for this gene. [provided by RefSeq, Dec 2011],
UniProt
Q9UBC5
Swiss Prot
Q9UBC5
Reactivity
Human; Rat; Mouse
Immunogen
Synthesized peptide derived from human protein . at AA range: 370-450
Target
MYO1A
Clonality
Polyclonal
Source
Rabbit
Applications
WB; ELISA
Concentration
1 mg/ml
Dilution
WB 1:500-2000 ELISA 1:5000-20000
Buffer
-20°C/1 year
Molecular Weight
114kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
114kD
Fragment
IgG
Subcellular Location
Cytoplasm, microvillus, brush border, basal plasma membrane, basolateral plasma membrane, apical plasma membrane, lateral plasma membrane, myosin complex, cortical actin cytoskeleton, filamentous actin, plasma membrane raft
Gene ID (Human)
4640

UniProtKB · Q9UBC5

Unconventional myosin-Ia

MYO1A_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q9UBC5
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
MYO1A
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
—
Secondary accessions
Q9UQD7
Protein keywords

Molecular function

Actin-bindingCalmodulin-bindingMotor proteinMyosin

Ligand

ATP-bindingNucleotide-binding

Cellular component

Cell projection

PTM

Phosphoprotein

Technical term

Proteomics identificationReference proteome

Domain

Repeat

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