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MRAP rabbit pAb

CAT: 0855-ES9795-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0855-ES9795-01Size:50 µL
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Background
Melanocortin 2 receptor accessory protein (MRAP) Homo sapiens This gene encodes a melanocortin receptor-interacting protein. The encoded protein regulates trafficking and function of the melanocortin 2 receptor in the adrenal gland. The encoded protein can also modulate signaling of other melanocortin receptors. Mutations in this gene have been associated with familial glucocorticoid deficiency type 2. Alternatively spliced transcript variants have been described. [provided by RefSeq, Dec 2009]
Description
Melanocortin 2 receptor accessory protein (MRAP) Homo sapiens This gene encodes a melanocortin receptor-interacting protein. The encoded protein regulates trafficking and function of the melanocortin 2 receptor in the adrenal gland. The encoded protein can also modulate signaling of other melanocortin receptors. Mutations in this gene have been associated with familial glucocorticoid deficiency type 2. Alternatively spliced transcript variants have been described. [provided by RefSeq, Dec 2009],
UniProt
Q8TCY5
Swiss Prot
Q8TCY5
Reactivity
Human; Rat; Mouse
Immunogen
Synthesized peptide derived from human protein . at AA range: 20-100
Target
MRAP
Clonality
Polyclonal
Source
Rabbit
Applications
WB; ELISA
Concentration
1 mg/ml
Dilution
WB 1:500-2000 ELISA 1:5000-20000
Buffer
-20°C/1 year
Molecular Weight
18kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
18kD
Fragment
IgG
Subcellular Location
Cell membrane ; Single-pass membrane protein . Endoplasmic reticulum membrane ; Single-pass membrane protein . The formation of antiparallel homo- and heterodimers suggest that N- and C-terminus can both localize in the cytoplasmic and extracellular parts, depending on the context (PubMed:20371771) . Upon insulin stimulation, it is redistributed into spotty structures throughout the cytoplasm. .
Gene ID (Human)
56246

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