EDC4 rabbit pAb

• Background :

  Function:In the process of mRNA degradation, seems to play a role in mRNA decapping. Component of a complex containing DCP2 and DCP1A which functions in decapping of ARE-containing mRNAs. Promotes complex formation between DCP1A and DCP2. Enhances the catalytic activity of DCP2 (in vitro) ., PTM:Phosphorylated upon DNA damage, probably by ATM or ATR., similarity:Belongs to the WD repeat EDC4 family., similarity:Contains 4 WD repeats., subunit:Part of a decapping complex consisting of DCP1A, DCP2, EDC3, EDC4 and probably DDX6. Part of a complex consisting of DCP1A, EDC3, EDC4 and DDX6. Part of a complex consisting of DCP1B, EDC3, EDC4 and DDX6. Interacts with DCP2.

• Description :

  Function: In the process of mRNA degradation, seems to play a role in mRNA decapping. Component of a complex containing DCP2 and DCP1A which functions in decapping of ARE-containing mRNAs. Promotes complex formation between DCP1A and DCP2. Enhances the catalytic activity of DCP2 (in vitro). PTM: Phosphorylated upon DNA damage, probably by ATM or ATR. similarity: Belongs to the WD repeat EDC4 family. similarity: Contains 4 WD repeats. subunit: Part of a decapping complex consisting of DCP1A, DCP2, EDC3, EDC4 and probably DDX6. Part of a complex consisting of DCP1A, EDC3, EDC4 and DDX6. Part of a complex consisting of DCP1B, EDC3, EDC4 and DDX6. Interacts with DCP2.

• UniProt :

  Q6P2E9

• Swiss Prot :

  Q6P2E9

• Reactivity :

  Human; Mouse; Rat

• Immunogen :

  Synthesized peptide derived from part region of human protein

• Clonality :

  Polyclonal

• Source :

  Rabbit

• Applications :

  WB; ELISA

• Concentration :

  1 mg/ml

• Dilution :

  WB 1:500-2000 ELISA 1:5000-20000

• Molecular Weight :

  154kD

• Storage Conditions :

  -20°C/1 year

• Observed Molecular Weight :

  154kD

• Fragment :

  IgG

• Subcellular Location :

  Cytoplasm, P-body . Nucleus .

• Gene ID (Human) :

  23644